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doi: 10.1172/JCI58196 28 BedardKKrauseKH

Formula: C 14 H 24 CuN 6 O 4 Molecular Weight (MW): 403.9 g/mol Dose: 100 mg Purity: 98% (HPLC) Storage: 20C, protect from light Documentation: COA + HPLC + Mass Spec Research Use Declaration This material is supplied exclusively for in-vitro and pre-clinical laboratory research purposes

The extracellular L-cysteine/L-cystine redox balance, and thus the synthesis of GSH, is finely regulated by the intracellular conversion of L-cystine into L-cysteine (10), and its impairment is related to oxidative stress and other pathological disorders

It also does not establish gamma-linkage identity, GSSG content, endotoxin control, sterility, particulate quality or suitability for a particular route

Briefly, the muscle biopsy was first weighed and then cut in ice-cold isolation medium (100 mM sucrose, 100 mM KCl, 50 mM Tris-HCl, 1 mM KH 2 PO 4 , 100 M EGTA, 0.1% BSA

Both protocols use a before-bed injection and run concurrently without modification to either schedule