In Studies 1 and 2, all patients received a standard lifestyle intervention which included instruction on a reduced-calorie diet (approximately 500 kcal/day deficit) and increased physical activity counseling (recommended minimum of 150 min/week) that began with the first dose of study medication or placebo and continued throughout the trial
How to use IMFERON INJECTION IMFERON INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or into a muscle as an intramuscular injection
By adjusting B12 doses for each patient, doctors can make treatments better and improve life quality
Studies typically use once-daily administration , often morning on empty stomach before activity to maximise the lipolytic window
10.1038/s43587-020-00006-2 47 RobertsR
Seek medical advice if you experience: New-onset insomnia or significant sleep disruption that persists after starting B12 supplementation Paradoxical fatigue : Worsening tiredness despite taking B12, which may indicate an underlying condition requiring investigation Neurological symptoms : Tingling, numbness, balance problems, or cognitive changes, which could suggest B12 deficiency or other neurological conditions Mood changes : Anxiety, agitation, or depression that develops or worsens after starting supplementation Palpitations or rapid heartbeat : Though rare, some individuals report cardiovascular symptoms that should be evaluated It's important to note that sleep disturbances may be unrelated to B12 supplementation
