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Aphthous stomatitis Aphthous stomatitis , [2] or recurrent aphthous stomatitis ( RAS ), commonly referred to as a canker sore or salt blister , is a common condition characterized by the repeated formation of benign and non-contagious mouth ulcers (aphthae) in otherwise healthy individuals

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The antigenic epitope is collected by dermal dendritic cells and Langerhans cells, the antigen-presenting cells (APC) of the skin, and undergo maturation and migration to regional lymph nodes

Michelle Kelman, a lecturer at the UCLA School of Dentistry, says "When in doubt, you need to look at the bristles." She adds, "If the bristles are frayed, it's time for a new toothbrush." When a toothbrush is old and overused, it becomes much less effective at removing food particles and bacteria from your teeth