glutathione s transferase and oxidative stress

glutathione s transferase and oxidative stress S-Transferases in Cancer Glutathione S-Transferase - an overview

Name: glutathione s transferase and oxidative stress S-Transferases in Cancer Glutathione S-Transferase - an overview
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To TL, Cuadros AM, Shah H, Hung WHW, Li Y, Kim SH, Rubin DHF, Boe RH, Rath S, Eaton JK, et al

Healthy cells maintain a remarkable GSH to GSSG ratio exceeding 100:1

Lowering glutamine levels to 50% of the standard culture concentration significantly inhibits mouse T cell proliferation, while reducing it to below 10% completely blocks proliferation [131]

This finding is surprising because asparagine supplementation does not restore the levels of other NEAAs (alanine, proline, and glutamate) or any TCA cycle intermediates (-KG, malate, and fumarate)