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Mitochondrial respiration was determined as described 69,70 and detailed under Mitochondrial respiration assays. Statistics Statistical tests were performed using Prism v10.0 (GraphPad Software, San Diego, CA) and are indicated in figure legends

Our study is first to demonstrate novel molecular mechanisms involved in the sensitization of PTC cells to ferroptosis inducer- we show that RSL3, a potent direct GPX4 inhibitor, effectively reduces the viability of thyroid cancer lines with various mutational backgrounds compared to HThF control cell line in a dose-dependent manner

About The Author Medically reviewed by Dr

[Google Scholar] Diamond I, Gordon AS (1997)

Carcinogenesis 21 (3), 485495

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