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Weight loss is the cornerstone of care

The fasted state is criticalinsulin suppresses NNMT activity, so dosing during fed states reduces 5-Amino-1MQ's efficacy

*Correspondence: Giovanni Barbara [email protected] This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers