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Phase 1b/2 study of binimetinib (BINI) in combination with nivolumab (NIVO) or NIVO plus ipilimumab (IPI) in patients (pts) with previously treated microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) with RAS mutation

Those cases, in which antioxidant therapy has been shown to have a positive effect, will also be discussed

Proline-hydroxylated hypoxia-inducible factor 1 (HIF-1) upregulation in human tumours

Jama 2005, 294, (17), 2228-30, 10.1001/jama.294.17.2228

Zureik M, Galan P, Bertrais S, Mennen L, Czernichow S, Blacher J, Ducimetiere P, Hercberg S

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