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The GABRB3 gene, which encodes the 3 subunit of the GABA receptor, is essential for this balance

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A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates AD disease pathology and restores neurogenesis

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The disclosure further relates to a pharmaceutical composition comprising an antibodydrug conjugate as disclosed herein, in combination with one or more pharmaceutical acceptable excipient, diluent or carrier, optionally comprising other active ingredients, for example anti-cancer drugs or immunotherapeutic drugs such as immune checkpoint inhibitors

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