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Description

It is not an FDA-approved treatment and not a clinical designation

Nagalingam A, et al

[Abstract]2025 Jun 25:1-11

hAAT undergoes oxidative modification in high-ROS environments, which alters its functional properties

Additionally, CKD is linked to hyperphosphatemia, which triggers senescence in myoblasts, endothelial cells, and vascular smooth muscle cells, consequently fostering sarcopenia and vascular calcification

Nevertheless, evidence (79,121) elucidating the precise mechanisms and interactions between GGT and ChaC1/ChaC2 and initiation and promotion of autophagy remains limited