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6.3 Metabolic diseases Aging imposes progressive physiological changes that compromise metabolic homeostasis and increase susceptibility to the development of conditions such as insulin resistance, visceral obesity, and type 2 diabetes (T2D) (Poggiogalle et al., 2018)

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showed that deleting or over-expressing GPX4 respectively intensified or blocked the injury produced by ferroptosis-inducing compounds

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Alkylene used alone or as part of alkylene glycol for example, refers to a divalent saturated, straight-chained or branched alkyl group as defined herein