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Studies in growth hormone-deficient mice show that while other growth hormone secretagogues increased body fat through growth hormone-independent mechanisms that included increased feeding, ipamorelin's effects on body composition are primarily mediated through its growth hormone-releasing properties

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The binding-induced conformational changes may facilitate the activation of G-proteins, which are signaling proteins hypothesized to be found on the intracellular side of the GHRH receptor

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Sermorelin injections are typically administered subcutaneously (under the skin) using a small needle in your thigh, abdomen, or upper arm

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