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The first is idiopathic hypercalciuria

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM

The two conditions can coexist but have different anatomical origins, hormonal drivers, and treatment approaches

Confusingly, both are marketed to researchers under the umbrella of IGF-1 variants, and the naming overlap has fostered a persistent misconception that they are interchangeable or that they work by the same route