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10.1073/pnas.252461999 Proc

Other enzymes, including CYP27A1, CYP3A4, and CYP2J3, may also contribute in tissue-specific contexts to maintain 25-hydroxylation homeostasis [89]

In this device, microbes were separated from the human cells by a nanoporous membrane with an artificial mucus layer, and even under these conditions, the co-cultures were only maintained for 48 hours