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As also the enzymes HGPRT (converts hypoxanthine to IMP) and adenylosuccinate synthase and adenylosuccinate lysase (amidate IMP to AMP) are expressed in astrocytes [236], it can be assumed that also inosine can serve as extracellular precursor for AMP synthesis and subsequently for ATP restoration

"Its quite frustrating as a clinician to not be able to prescribe the substance for them to use at home and on a daily basis, which is what they need," said Bull, adding the recommended protocol is twice a day for 30 to 60 days

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The key takeaway is that GHK-CU produces measurable, documented improvements when used consistently at appropriate doses

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