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These findings indicate that the livers of PD mouse models are affected by -syn aggregation, and -syn may propagate from the brain to the liver, subsequently inducing hepatic inflammation [42]

They may also affect multiple signaling pathways simultaneously, which could synergistically enhance their efficacy in the treatment of endometriosis

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Moreover, cell typespecific differences in regenerative capacity, metabolic state, and expression of death-regulatory factors impose additional constraints, resulting in distinct PCD outcomes across different cellular contexts

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