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Elution of the bound protein is caused by displacement with imidazole or low pH conditions

Because iron is indispensable for wrapping myelin and powering metabolic enzymes, oligodendrocytes outrank every other CNS cell population in intracellular iron content (Friedrich et al., 2021

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You can't supplement your way around a suppressed hypothalamic-pituitary axis

For example, Lo and colleagues (2016) reported that obesity failed to promote tumorigenesis in localized patient-derived prostate cancer xenografts in severe combined immunodeficiency (SCID) mice (13)